rQ JOURNAL

Do you frequently experience low motivation for sex?
When desire fades, most women assume it is stress, a busy season, or simply getting older. Those can all play a part. Often, though, the change also lines up with a hormone most people link only to men. Women make testosterone too, and even in small amounts it shapes how much drive, strength, and resilience you feel day to day.
Women run on testosterone too
Testosterone is an androgen, a hormone family best known for building muscle and fueling desire. In women it comes from the ovaries and the adrenal glands, the small glands on top of your kidneys that also make cortisol. Women produce roughly a tenth to a twentieth of what men do, yet in a typical woman testosterone circulates at higher levels than estrogen.
Most of it travels bound to a carrier protein called sex hormone binding globulin, or SHBG. Only the unbound portion can enter your cells and act. That detail matters, because two women with the same total testosterone can feel very different depending on how much SHBG is holding it back.
What testosterone does in a woman's body
Desire and arousal: testosterone acts on the brain's reward and motivation circuits and on blood flow to sexual tissue, which is why it is the hormone most closely tied to a woman's sexual interest.
Muscle and strength: it helps you build and hold lean muscle, which in turn protects your metabolism and blood sugar control.
Bone: it supports bone density directly and through its conversion to estrogen, a key reason levels matter after menopause.
Mood and motivation: healthy levels support confidence, focus, and a steady sense of get up and go.
Body composition: balanced testosterone favors muscle over fat storage, especially around the midsection.
Why levels drift low
Testosterone in women peaks in the twenties and falls gradually, so a woman in her forties often has about half of what she had at twenty. The drop is steeper after surgical removal of the ovaries. Other common drains include oral birth control and oral estrogen, which raise SHBG and tie up more of what you make; long stretches of high stress, since cortisol and testosterone draw on the same adrenal raw materials; under-eating or very low fat diets; low thyroid output; poor sleep; and certain medications, including some antidepressants and opioids.
When levels run high
The opposite problem is common too. Polycystic ovary syndrome, or PCOS, is the most frequent cause of excess androgens in women, and it is tightly linked with insulin resistance, because high insulin signals the ovaries to make more testosterone and lowers SHBG at the same time. Signs include irregular cycles, acne along the jaw, thinning scalp hair, and coarse hair on the face or chest. Balancing blood sugar is often the most powerful lever here.
Genes that shape how you handle testosterone
Everyone has the genes that build, carry, and convert testosterone. The issue is the variant you carry and how fast it runs. The CYP19A1 gene makes aromatase, the enzyme that converts testosterone into estrogen. A faster variant, especially combined with extra body fat and inflammation, can pull testosterone down while pushing estrogen up. Variants in the SHBG gene change how much carrier protein you make, and the CYP3A4 and UGT pathways in your liver affect how efficiently used hormones are cleared. Knowing your variants explains why the same lab number can mean different things for different women.
Practical next steps
Start with labs: ask for total testosterone, bioavailable testosterone, and SHBG, ideally drawn in the morning and, if you still cycle, in the first week after your period starts. Add DHEA-S, estradiol, progesterone, a full thyroid panel, morning cortisol, fasting insulin, fasting glucose, and HbA1c so the result has context.
Support production with nutrition: eat enough total calories and protein, around 25 to 30 grams per meal, and include healthy fats from eggs, olive oil, avocado, wild fish, and grass-fed meats, since cholesterol is the starting material for every sex hormone. Zinc from oysters, beef, and pumpkin seeds, magnesium, vitamin D, and boron are the minerals and vitamins most often low when testosterone is low.
Consider targeted supplements: zinc picolinate (15 to 30 milligrams daily with food), magnesium glycinate in the evening, vitamin D3 with K2 dosed to your blood level, and an adaptogen such as ashwagandha, which has been studied for stress and sexual function in women. DHEA can raise testosterone in women with low levels, but it should be dosed low and guided by your labs and clinician. If your levels run high, inositol (a 40 to 1 blend of myo and D-chiro inositol) and spearmint tea have research support in PCOS.
Lift and recover: strength training two to three times a week is the most reliable natural way to support healthy androgen levels and muscle. Pair it with 7 to 9 hours of sleep, since most daily testosterone release happens during deep sleep, and cut back on alcohol, which speeds the conversion of testosterone to estrogen.
Talk to your clinician about therapy when needed: for postmenopausal women with distressing changes in sexual function, low dose transdermal testosterone has the strongest evidence. It should be prescribed in female doses with follow-up labs.
The rQ Perspective
A fading sex life, lost strength, and flat motivation rarely trace back to one hormone working alone. Testosterone sits in a network with cortisol, insulin, thyroid, estrogen, liver clearance, and the genes that set the pace of each step. When you can see which of those links is pulling your levels off course, the fix becomes specific instead of a guess.
The rQ assessment is the most comprehensive functional medicine assessment on the market. It gives a clinical-grade look at your genes, detox pathway function, and drivers of illness such as pathogens, and it helps you understand your body. Take the rQ assessment at www.rq.one.
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